Synthesis and bioactivity investigation of benzophenone and its derivatives-Reference-Cited by-同舟云学术

Synthesis and bioactivity investigation of benzophenone and its derivatives

Published:2024 Issue:28 Volume:14 Page:20339-20350
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lei Chun¹²³,Yang Wanjing¹²³,Lin Ziyu¹²³,Tao Yuyan²³,Ye Renping²³,Jiang Yucai⁴,Chen Yuli²³,Zhou Beidou¹²³^ORCID

Affiliation:

1. School of Pharmacy, Fujian Medical University, Fuzhou 350108, China

2. School of Pharmacy and Medical Technology, Putian University, Putian 351100, China

3. Key Laboratory of Pharmaceutical Analysis and Laboratory Medicine (Putian University), Fujian Province University, Putian 351100, China

4. The Affiliated Hospital (Group) of Putian University, Putian 351100, China

Abstract

Several benzophenones and their derivatives were synthesised, and most of which showed antitumour activity, especially compound 1. Therefore, the antitumour mechanism of compound 1 was investigated through network pharmacology and molecular docking.

Funder

Natural Science Foundation of Fujian Province

Putian Science and Technology Bureau

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA02797C

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