Protein/peptide secondary structural mimics: design, characterization, and modulation of protein–protein interactions-Reference-Cited by-同舟云学术

Protein/peptide secondary structural mimics: design, characterization, and modulation of protein–protein interactions

Published:2016 Issue:66 Volume:6 Page:61599-61609
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Zhipeng A.¹²³⁴⁵,Ding Xiaozhe Z.¹⁶⁷⁴⁸,Tian Chang-Lin¹²³⁴,Zheng Ji-Shen¹²³⁴

Affiliation:

1. School of Life Sciences

2. University of Science and Technology of China

3. Hefei 230026

4. China

5. Department of Chemistry

6. Tsinghua University

7. Beijing 100084

8. Department of Bioengineering

Abstract

This review discusses general aspects of novel artificial peptide secondary structure mimics for modulation of PPIs, their therapeutic applications and future prospects.

Funder

Natural Science Foundation of Anhui Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA13976K

Reference165 articles.

1. Peptide based Molecules as Protein-Protein Interaction Inhibitors: Tools for Chemical Genetics and Therapy

2. Towards a proteome-scale map of the human protein–protein interaction network

3. Protein surface recognition and proteomimetics: mimics of protein surface structure and function

4. Reaching for high-hanging fruit in drug discovery at protein–protein interfaces

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