An ultrasensitive homogeneous electrochemical biosensor based on CRISPR-Cas12a

Author:

Liu Jie12345,Wan Qing12345,Zeng Ruijin678910,Tang Dianping678910ORCID

Affiliation:

1. Hubei Key Laboratory of Radiation Chemistry and Functional Materials

2. School of Nuclear Technology and Chemistry & Biology

3. Hubei University of Science and Technology

4. Xianning 437100

5. P. R. China

6. Key Laboratory for Analytical Science of Food Safety and Biology (MOE & Fujian Province)

7. State Key Laboratory of Photocatalysis on Energy and Environment

8. Department of Chemistry

9. Fuzhou University

10. Fuzhou 350116

Abstract

A simple and immobilization-free homogeneous electrochemical biosensor for the detection of human papillomavirus (HPV-16) has been fabricated by combining with methylene blue (MB)-labeled probes toward the negatively-charged indium tin oxide (ITO) electrode.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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