Specific zinc binding to heliorhodopsin-Reference-Cited by-同舟云学术

Specific zinc binding to heliorhodopsin

Published:2023 Issue:4 Volume:25 Page:3535-3543
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Hashimoto Masanori¹,Miyagawa Koichi²^ORCID,Singh Manish¹,Katayama Kota¹³⁴,Shoji Mitsuo²⁴^ORCID,Furutani Yuji¹³^ORCID,Shigeta Yasuteru²^ORCID,Kandori Hideki¹³^ORCID

Affiliation:

1. Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Showa-ku, Nagoya 466-8555, Japan

2. Center for Computational Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan

3. OptoBioTechnology Research Center, Nagoya Institute of Technology, Showa-ku, Nagoya 466-8555, Japan

4. JST-PRESTO, Kawaguchi, Saitama 332-0012, Japan

Abstract

ATR-FTIR spectroscopy of heliorhodopsin mutants revealed E150 to be responsible for Zn2+-binding. Molecular dynamics simulations built a coordination structure of Zn2+, where E150 and protein bound water molecules participate direct coordination.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CP/D2CP04718G

Reference55 articles.

1. Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms

2. A distinct abundant group of microbial rhodopsins discovered using functional metagenomics