Molecular docking and dynamics based approach for the identification of kinase inhibitors targeting PI3Kα against non-small cell lung cancer: a computational study-Reference-Cited by-同舟云学术

Molecular docking and dynamics based approach for the identification of kinase inhibitors targeting PI3Kα against non-small cell lung cancer: a computational study

Published:2022 Issue:33 Volume:12 Page:21452-21467
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Halder Debojyoti¹,Das Subham¹^ORCID,R. Aiswarya¹^ORCID,R. S. Jeyaprakash¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka-576104, India

Abstract

Non-small cell lung cancer (NSCLC) is an obscure disease whose incidence is increasing worldwide day by day, and PI3Kα is one of the major targets for cell proliferation due to the mutation.

Funder

Manipal Academy of Higher Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA03451D

Reference35 articles.

1. Artificial intelligence in drug discovery and development

2. Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective

3. Structure-Activity Relationship Insight of Naturally Occurring Bioactive Molecules and Their Derivatives Against Non-Small Cell Lung Cancer: A Comprehensive Review

4. Targeting the PI3K/Akt/mTOR pathway in non‐small cell lung cancer (NSCLC)

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