Development of a high-throughput and sensitive assay of fusion genes in lung cancer by array-based MALDI-TOFMS

Author:

Wu Han-Tao12345,Li Kun12345,Wang Gang12345,Yang Xue-Xi12345,Zhu Anna678,Xu Xu-Ping678,Li Ming12345,Wu Ying-Song12345,Liu Tian-Cai12345ORCID

Affiliation:

1. Institute of Antibody Engineering

2. School of Laboratory Medicine and Biotechnology

3. Southern Medical University

4. Guangzhou 510515

5. P. R. China

6. Guangzhou Darui Biotechnology Co. Ltd.

7. Guangzhou 510665

8. China

Abstract

This study established a high-throughput, sensitive and cost-effective method to detect three lung fusion genes of 96 samples at one time.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference36 articles.

1. Lung Cancer: Epidemiology, Etiology, and Prevention

2. Cancer statistics, 2013

3. Clinical Characteristics of 274 Non-Small Cell Lung Cancer Patients in China

4. H.Wakelee , K.Kelly , M. J.Edelman , 50 Years of Progress in the Systemic Therapy of Non-Small Cell Lung Cancer , American Society of Clinical Oncology Educational Book , 2014 , vol. 34 , pp. 177–189

5. Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

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