The enzymatic synthesis of lactose caprate using Candida rugosa lipase immobilized into ZIF-8 and investigation of its anticancer applications against K562 leukemia and HeLa cancer cells

Author:

Karimian Effat1,Marandi Afsaneh1ORCID,Kardanpour Reihaneh1,Rafiei Sara1,Amirghofran Zahra2,Tangestaninejad Shahram1ORCID,Moghadam Majid1ORCID,Mirkhani Valiollah1,Mohammadpoor-Baltork Iraj1ORCID

Affiliation:

1. Department of Chemistry, Catalysis Division, University of Isfahan, Isfahan 81746-73441, Iran

2. Immunology Department, Autoimmune Diseases Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract

Lactose caprate was enzymatically synthesized using lipase immobilized into ZIF-8 and applied as an anticancer agent against K562 leukemia and HeLa cancer cells.

Funder

University of Isfahan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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