Rapid detection of major Gram-positive pathogens in ocular specimens using a novel fluorescent vancomycin-based probe-Reference-Cited by-同舟云学术

Rapid detection of major Gram-positive pathogens in ocular specimens using a novel fluorescent vancomycin-based probe

Published:2022 Issue:5 Volume:1 Page:1014-1020
ISSN:2635-0998
Container-title:Sensors & Diagnostics
language:en
Short-container-title:Sens. Diagn.

Author:

Sharma Richa¹^ORCID,Rajagopalan Harinee²,Klausen Maxime¹^ORCID,Jeyalatha Mani Vimalin²,Üçüncü Muhammed¹³^ORCID,Venkateswaran Seshasailam¹,Anand Appakkudal R.²,Bradley Mark¹^ORCID

Affiliation:

1. EaStCHEM, School of Chemistry, University of Edinburgh, King's Buildings, Edinburgh, EH9 3FJ, UK

2. L & T Microbiology Research Centre, Medical Research Foundation, Sankara Nethralaya, Chennai, India

3. Department of Analytical Chemistry, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Turkey

Abstract

A novel probe, based on vancomycin and 4-nitrobenzoxadiazole was synthesized and characterized, and used for the rapid and specific detection of Gram positive bacteria – the major pathogens responsible for eye infections in ocular specimens.

Funder

Science and Engineering Research Board

Royal Society

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SD/D2SD00061J

Reference25 articles.

1. Bacterial profile of ocular infections: a systematic review

2. Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance

3. Targeted imaging of bacterial infections: advances, hurdles and hopes

4. Fluorescent antibiotics for real-time tracking of pathogenic bacteria

5. Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

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