Enhanced performance of macrophage-encapsulated nanoparticle albumin-bound-paclitaxel in hypo-perfused cancer lesions

Author:

Leonard Fransisca123,Curtis Louis T.456,Yesantharao Pooja123,Tanei Tomonori123,Alexander Jenolyn F.123,Wu Min789,Lowengrub John10111213,Liu Xuewu123,Ferrari Mauro123,Yokoi Kenji123,Frieboes Hermann B.456,Godin Biana123

Affiliation:

1. Houston Methodist Research Institute

2. Department of Nanomedicine

3. R8-213, Houston, USA

4. University of Louisville

5. Department of Bioengineering

6. Louisville, USA

7. Northwestern University

8. Department of Engineering Sciences and Applied Mathematics

9. Chicago, USA

10. University of California

11. Irvine

12. Department of Mathematics

13. Irvine, USA

Abstract

The proposed experimental/computational approach could enable prediction of nanotherapeutics performance to treat hypovascularized metastatic cancer in the liver.

Funder

National Science Foundation

National Institutes of Health

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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