Pharmacophore modeling, docking and the integrated use of a ligand- and structure-based virtual screening approach for novel DNA gyrase inhibitors: synthetic and biological evaluation studies-Reference-Cited by-同舟云学术

Pharmacophore modeling, docking and the integrated use of a ligand- and structure-based virtual screening approach for novel DNA gyrase inhibitors: synthetic and biological evaluation studies

Published:2021 Issue:55 Volume:11 Page:34462-34478
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mathpal Deepti¹,Masand Mukesh²,Thomas Anisha³,Ahmad Irfan⁴,Saeed Mohd⁵,Zaman Gaffar Sarwar⁴,Kamal Mehnaz⁶,Jawaid Talha⁷,Sharma Pramod K.²,Gupta Madan M.⁸,Kumar Santosh⁹,Srivastava Swayam Prakash¹¹⁰¹¹,Balaramnavar Vishal M.¹^ORCID

Affiliation:

1. Sanskriti University, School of Pharmacy and Research, 28 KM. Stone, Mathura – Delhi Highway, Chhata, Mathura, Uttar Pradesh (UP), 281401, India

2. Department of Pharmacy, Faculty of Medicine and Allied Sciences, Galgotias University, Gautam Buddha Nagar, Uttar Pradesh, 226001, India

3. Department of Chemistry, School of Advanced Sciences, VIT, Vellore, India

4. Department of Clinical Laboratory Science, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia

5. Department of Biology College of Sciences, University of Hail, Saudi Arabia

6. Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box No. 173, Al Kharj 11942, Kingdom of Saudi Arabia

7. Department of Pharmacology, College of Medicine, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Kingdom of Saudi Arabia

8. School of Pharmacy, Faculty of the West Indies St Augustine, Trinidad and Tobago, West Indies

9. Government Degree College, Hansaur, Barabanki, Uttar Pradesh (UP), 225415, India

10. Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06520, USA

11. Vascular Biology and Therapeutic Program, Yale University School of Medicine, New Haven, CT, 06511, USA

Abstract

Fluoroquinolones, a class of compound, act via inhibiting DNA gyrase and topoisomerase IV enzymes.

Funder

King Khalid University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05630A

Reference51 articles.

1. Global epidemiology of tuberculosis

2. P.Pahal and S.Sharma , in StatPearls , StatPearls Publishing , 2020

3. New fronts in an old war

4. Global Epidemiology of Tuberculosis and Progress Toward Achieving Global Targets — 2017

5. HIV and tuberculosis: A historical perspective on conflicts and challenges

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Algebraic Modeling System for Supporting Research in Medicine and Pharmacology;2023 IEEE 12th International Conference on Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications (IDAACS);2023-09-07

2. In Silico Studies, Design and Synthesis of Novel Fused Pyrimidine Derivatives as a DNA Gyrase Inhibitor and Antibacterial Activity Against Quinolone Resistant Escherichia Coli;Journal of Computational Biophysics and Chemistry;2023-07-21

3. Molecular modeling in the radiation therapy. The algebraic approach;PROBLEMS IN PROGRAMMING;2022-12

4. Algebraic Approach in Molecular Modeling;2022 International Conference on Electrical, Computer, Communications and Mechatronics Engineering (ICECCME);2022-11-16