Transformation of phytosterols into pregnatetraenedione by a combined microbial and chemical process-Reference-Cited by-同舟云学术

Transformation of phytosterols into pregnatetraenedione by a combined microbial and chemical process

Published:2022 Issue:9 Volume:24 Page:3759-3771
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Liu Yong-Jun¹,Ji Wei-ting¹,Song Lu¹,Tao Xin-Yi¹,Zhao Ming¹,Gao Bei¹^ORCID,Meng Hao²,Wang Feng-Qing¹^ORCID,Wei Dong-Zhi¹^ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China

2. Hunan Norchem Pharmaceutical Co. Ltd, Changde 415400, China

Abstract

A 9-0HPDC-M hyperproducing strain with high selectivity and yield was constructed and a more efficient route to produce corticosteroids from the phytosterols via pregnatetraenedione was proposed.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Natural Science Foundation of Shanghai

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D1GC04819H

Reference46 articles.

1. Expedient synthesis of 17α,21-dihydroxy-9β,11β-epoxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate from prednisolone utilising a novel Mattox rearrangement