Enantioselective Michael addition of aldehydes to maleimides catalysed by surface-adsorbed natural amino acids

Author:

Kozma Viktória1,Szőllősi György2ORCID

Affiliation:

1. Department of Organic Chemistry, University of Szeged, 6720 Szeged, Dóm tér 8, Hungary

2. SZTE-ELKH Stereochemistry Research Group, University of Szeged, 6720 Szeged, Eötvös utca 6, Hungary

Abstract

Chiral hybrid materials obtained by adsorption of primary α-amino acids on the surface of inorganic oxides are economic, recyclable, highly enantioselective heterogeneous catalysts for the Michael addition of aldehydes toN-substituted maleimides.

Funder

Emberi Eroforrások Minisztériuma

Hungarian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Reference97 articles.

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4. V.Šunjić and M. J.Parnham , Signposts to Chiral Drugs, Organic Synthesis in Action , Springer Basel AG , Basel , 2011

5. Asymmetric Catalysis on Industrial Scale, Challenges, Approaches and Solutions , ed. H. U. Blaser and E. Schmidt , Wiley-VCH, Verlag GmbH , Weinheim , 2004

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