Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation-Reference-Cited by-同舟云学术

Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation

Published:2018 Issue:10 Volume:5 Page:1622-1627
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Di Gregorio Giovanni¹²³⁴^ORCID,Mari Michele¹²³⁴^ORCID,Bartolucci Silvia¹²³⁴^ORCID,Bartoccini Francesca¹²³⁴^ORCID,Piersanti Giovanni¹²³⁴^ORCID

Affiliation:

1. Department of Biomolecular Sciences

2. University of Urbino “Carlo Bo”

3. 61029 Urbino

4. Italy

Abstract

Oxindoles react with N-acetyl amino alcohols to form tryptamine-derived oxindoles, whereas analogous reactions with N-alkyl amino alcohols lead to lactam formation via a relatively mild borrowing hydrogen process.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00184G

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