Novel 1,3,5-triazine-based pyrazole derivatives as potential antitumor agents and EFGR kinase inhibitors: synthesis, cytotoxicity, DNA binding, molecular docking and DFT studies

Author:

Raghu M. S.123,Pradeep Kumar C. B.453,Prashanth M. K.673ORCID,Yogesh Kumar K.893,Prathibha B. S.673,Kanthimathi G.10113,Alissa Siham Abdulrahman121314,Alghulikah Hanan Abdulrahman121314,Osman Sameh M.151614

Affiliation:

1. Department of Chemistry, New Horizon College of Engineering

2. Bengaluru 560 103

3. India

4. Department of Chemistry, Malnad College of Engineering

5. Hassan 573 202

6. Department of Chemistry, B N M Institute of Technology

7. Bengaluru 560 070

8. Department of Chemistry, School of Engineering and Technology, Jain University

9. Ramanagara

10. Department of Chemistry, Ramco Institute of Technology

11. Rajapalayam

12. Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University

13. Riyadh 11671

14. Saudi Arabia

15. Department of Chemistry, College of Science, King Saud University

16. Riyadh

Abstract

The development of new 1,3,5-triazine-based pyrazole derivatives as effective anticancer agents.

Funder

Princess Nourah Bint Abdulrahman University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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