A multifunctional substance P-conjugated chitosan hydrochloride hydrogel accelerates full-thickness wound healing by enhancing synchronized vascularization, extracellular matrix deposition, and nerve regeneration-Reference-Cited by-同舟云学术

A multifunctional substance P-conjugated chitosan hydrochloride hydrogel accelerates full-thickness wound healing by enhancing synchronized vascularization, extracellular matrix deposition, and nerve regeneration

Published:2021 Issue: Volume: Page:
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Li Hao¹²³⁴,Li Mengna⁵⁶⁷⁴,Liu Pei¹²³⁴,Wang Kaiyang¹²³⁴,Fang Haoyu¹²³⁴,Yin Junhui⁸²³⁴,Zhu Daoyu¹²³⁴,Yang Qianhao¹²³⁴,Gao Junjie¹²³⁴⁸,Ke Qinfei⁵⁶⁷⁴,Yu Hongping¹²³⁴⁹,Guo Yaping⁵⁶⁷⁴^ORCID,Gao Youshui¹²³⁴^ORCID,Zhang Changqing¹²³⁴

Affiliation:

1. Department of Orthopaedic Surgery

2. Shanghai Jiao Tong University Affiliated Sixth People's Hospital

3. Shanghai 200233

4. China

5. The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials

6. Shanghai Normal University

7. Shanghai 200234

8. Institute of Microsurgery on Extremities

9. The First Affiliated Hospital of Xiamen University

Abstract

The CSCl–SP hydrogel is a multifunctional platform with an ideal capacity to dramatically promote full-thickness wound healing by enhancing angiogenesis, extracellular matrix deposition and remodelling, and nerve fibre growth.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00357G

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