The unexpected racemization and hydrogen–deuterium exchange of the hydrogen at the α-carbon of proline analogs containing the 5-azoniaspiro[4.4]nonyl-group-Reference-Cited by-同舟云学术

The unexpected racemization and hydrogen–deuterium exchange of the hydrogen at the α-carbon of proline analogs containing the 5-azoniaspiro[4.4]nonyl-group

Published:2018 Issue:5 Volume:16 Page:825-831
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Setner B.¹²³⁴^ORCID,Wierzbicka M.¹²³⁴^ORCID,Jerzykiewicz L.¹²³⁴^ORCID,Lisowski M.¹²³⁴^ORCID,Szewczuk Z.¹²³⁴^ORCID

Affiliation:

1. Faculty of Chemistry

2. University of Wrocław

3. 50-383 Wrocław

4. Poland

Abstract

Herein, we present an unexpected racemization and the hydrogen–deuterium exchange (HDX) at the α-C atom of the proline derivative under basic aqueous conditions (1% water solution of triethylamine).

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02926H

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