Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS

Author:

Wei Mengying12345,Liu Zhongying6789,Liu Yuanyuan6789,Li Shizhe1011129,Hu Mingxin6789,Yue Kexin6789,Liu Tianshu6789,He Yang131415169,Pi Zifeng12345ORCID,Liu Zhiqiang12345,Song Fengrui12345ORCID

Affiliation:

1. State Key Laboratory of Electroanalytical Chemistry

2. National Center of Mass Spectrometry in Changchun

3. Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry

4. Changchun Institute of Applied Chemistry

5. Chinese Academy of Sciences

6. School of Pharmaceutical Sciences

7. Jilin University

8. Changchun 130021

9. China

10. Institute of Biomedical and Pharmaceutical Sciences

11. Guangdong University of Technology

12. Guangzhou 510006

13. Department of Pharmaceutical Analysis

14. School of Pharmacy and Food Science

15. Zhuhai College of Jilin University

16. Zhuhai 519041

Abstract

Schisandra chinensis (Turcz.) Baill (S. chinensis), a functional food, is used as a tonic and sedative agent in traditional Chinese medicine.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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