Asymmetric total synthesis of talienbisflavan A
Author:
Affiliation:
1. School of Marine Science and Technology
2. Harbin Institute of Technology
3. Weihai 264209
4. P. R. China
5. Beijing National Laboratory for Molecular Sciences
Abstract
The first asymmetric total syntheses of talienbisflavan A and bis-8,8′-epicatechinylmethane as well as a facile synthesis of bis-8,8′-catechinylmethane has been accomplished from readily available starting materials by using a newly developed direct regioselective methylenation of catechin derivatives as one of the key steps.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02837G
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