Dual-pore protocells with multitasking capacities for simultaneous delivery of therapeutic enzymes and drugs in macrophage depletion therapy-Reference-Cited by-同舟云学术

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Dual-pore protocells with multitasking capacities for simultaneous delivery of therapeutic enzymes and drugs in macrophage depletion therapy

Published:2024 Issue: Volume: Page:
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Parra-Nieto Jorge¹,Arroyo-Nogales Alicia¹,Marcos-Fernández Diana¹,Jimenez-Falcao Sandra¹,Arribas Carmen¹,Megias Diego²,Gonzalez-Murillo África³,Ramirez Manuel³,Baeza Alejandro¹^ORCID

Affiliation:

1. Dpto. Materiales y Producción Aeroespacial, ETSI Aeronáutica y del Espacio, Universidad Politécnica de Madrid, 28040 Madrid, Spain

2. Advanced Optical Microscopy unit, Instituto de salud Carlos III (ISCIII), Madrid, Spain

3. Servicio de Hematología y Oncología Pediátrica, Hospital Infantil Universitario Niño Jesús, Madrid, Spain

Abstract

Macrophages play a key role in tumour progression. Herein, novel multitasking protocells with capacity to deplete macrophages by the combined action of cytotoxic drug release, glucose starvation and oxygen generation are presented.

Funder

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D4BM00780H

Reference39 articles.

1. Cancer nanomedicine

2. Cancer nanomedicine: a review of nano-therapeutics and challenges ahead

3. Cancer nanotechnology: current status and perspectives

4. Tumor angiogenesis: causes, consequences, challenges and opportunities

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