Ricinodols A–G: new tetracyclic triterpenoids as 11β-HSD1 inhibitors from Ricinodendron heudelotii-Reference-Cited by-同舟云学术

Ricinodols A–G: new tetracyclic triterpenoids as 11β-HSD1 inhibitors from Ricinodendron heudelotii

Published:2015 Issue:34 Volume:5 Page:26777-26784
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yu Jin-Hai¹²³⁴⁵,Shen Yu¹²³⁴⁵,Wu Yan¹²³⁴⁵,Leng Ying¹²³⁴⁵,Zhang Hua¹²³⁴⁵,Yue Jian-Min¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Drug Research

2. Shanghai Institute of Materia Medica

3. Chinese Academy of Sciences

4. Shanghai 201203

5. People's Republic of China

Abstract

Chemical investigation of Ricinodendron heudelotii has returned seven new tetracyclic triterpenoids with moderate to significant inhibitory effect against 11β-HSD1 enzyme.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA01857A

Reference25 articles.

1. K. Plenderleith , in Ricinodendron heudelotii: A State of Knowledge Study undertaken for the Central African Regional Program for the Environment, Oxford Forestry Institute in University of Oxford, Oxford, 2000, pp. 1–44

2. Two dinorditerpenoids from Ricinodendron heudelotii

3. The functional roles of 11β-HSD1: vascular tissue, testis and brain

4. Obesity and corticosteroids: 11β-Hydroxysteroid type 1 as a cause and therapeutic target in metabolic disease

5. Dammarane-type triterpenoids as 11β-HSD1 inhibitors from Homonoia riparia

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