Construction of PEG-based amphiphilic brush polymers bearing hydrophobic poly(lactic acid) side chains via successive RAFT polymerization and ROP-Reference-Cited by-同舟云学术

Construction of PEG-based amphiphilic brush polymers bearing hydrophobic poly(lactic acid) side chains via successive RAFT polymerization and ROP

Published:2016 Issue:19 Volume:7 Page:3300-3310
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Qian Wenhao¹²³⁴,Song Xuemei⁵⁶⁷³⁴,Feng Chun⁵⁶⁷³⁴,Xu Peicheng¹²³⁴,Jiang Xue⁵⁶⁷³⁴,Li Yongjun⁵⁶⁷³⁴,Huang Xiaoyu⁵⁶⁷³⁴

Affiliation:

1. Department of Stomatology

2. Shanghai Xuhui District Dental Center

3. Shanghai 200032

4. People's Republic of China

5. Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules

6. Shanghai Institute of Organic Chemistry

7. Chinese Academy of Sciences

Abstract

This article reports the synthesis of PEG-b-(PAA-g-PLA) amphiphilic brush polymers by the combination of RAFT polymerization and organocatalytic ROP, which could self-assemble into spheres for sustained release of doxorubicin.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/PY/C6PY00189K

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