Rapid synthesis of carbonucleoside phophonate analogues as potential antiviral agents via a hydrophosphonylation reaction of ethynyl carbocyclic precursors
Author:
Affiliation:
1. Institut des Biomolécules Max Mousseron (IBMM)
2. UMR 5247
3. Université de Montpellier
4. CNRS
5. ENSCM
Abstract
Carbonucleoside phosphonate analogues were readily obtained using a free-radical hydrophosphonylation reaction under UV/Vis light irradiation of alkyne carbocyclic precursors.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C7NJ03991C
Reference22 articles.
1. Approved Antiviral Drugs over the Past 50 Years
2. l-Nucleoside enantiomers as antivirals drugs: A mini-review
3. Organic Chemist Whose Inventions Reshaped the Antiviral Drug World
4. Recent progress for the synthesis of selected carbocyclic nucleosides
5. Phosphonates as analogues of natural phosphates
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