Synthesis and properties of metal trifluoride complexes with amide-functionalised tacn macrocycles and radiofluorination of [GaF3(L1)] by 18F/19F isotopic exchange-Reference-Cited by-同舟云学术

Synthesis and properties of metal trifluoride complexes with amide-functionalised tacn macrocycles and radiofluorination of [GaF₃(L1)] by ¹⁸F/¹⁹F isotopic exchange

Published:2024 Issue:35 Volume:53 Page:14897-14909
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

O'Callaghan Charley¹,Greenacre Victoria K.¹^ORCID,King Rhys P.¹,Grigg Julian²,Herniman Julie M.¹,McRobbie Graeme²,Reid Gillian¹^ORCID

Affiliation:

1. School of Chemistry, University of Southampton, Southampton SO17 1BJ, UK

2. GE HealthCare, Pollards Wood, Nightingales Lane, Chalfont St Giles, Bucks, HP8 4SP, UK

Abstract

Three new amide-functionalised triaza-macrocyclic ligands and their complexes, fac-[MF3(L)] (M = Al, Ga, Fe), are described. Radiofluorination of [GaF3(L1)] in MeOH with aqueous [18F]F− gives ca. 20% radiochemical yield of [Ga18FF2(L1)].

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D4DT02074J

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