Modulating stem cell–chondrocyte interactions for cartilage repair using combinatorial extracellular matrix-containing hydrogels
Author:
Affiliation:
1. Department of Bioengineering
2. Stanford University
3. Stanford
4. USA
5. Department of Mechanical Engineering
6. Stanford School of Medicine
7. Drexel University
8. Philadelphia
9. Department of Orthopaedic Surgery
Abstract
Combinatorial ECM-containing hydrogels with decoupled mechanical and biochemical cues modulate cartilage formation by a stem cell and chondrocyte co-culture in 3D.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2016/TB/C6TB01583B
Reference50 articles.
1. A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects
2. Chondrogenic Differentiation of Adipose-Derived Stromal Cells in Combinatorial Hydrogels Containing Cartilage Matrix Proteins with Decoupled Mechanical Stiffness
3. Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype
4. Differential Maturation and Structure–Function Relationships in Mesenchymal Stem Cell- and Chondrocyte-Seeded Hydrogels
5. Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells
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