Dynamic kinetic resolution of atropisomeric N-arylindoles via chiral N-triflyl phosphoramide catalyzed asymmetric reductive amination-Reference-Cited by-同舟云学术

Dynamic kinetic resolution of atropisomeric N-arylindoles via chiral N-triflyl phosphoramide catalyzed asymmetric reductive amination

Published:2024 Issue:14 Volume:11 Page:3894-3899
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Shao You-Dong¹,Han Dan-Dan¹,Jiang Hong-Xin²,Zhou Xin-Yu²,Wang Wei-Kang¹,Zhang Jia-Xi¹,Liu Ya-Fei¹,Cheng Dao-Juan²^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Heze University, Heze 274015, China

2. School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China

Abstract

The first organocatalyzed asymmetric reductive amination towards axially chiral N-arylindoles proceeding through n → π* interaction-induced dynamic kinetic resolution is reported.

Funder

National Natural Science Foundation of China

Heze University

Anhui University of Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00616J

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