Liponitroxides: EPR study and their efficacy as antioxidants in lipid membranes

Author:

Mobbili Giovanna1234,Crucianelli Emanuela1234,Barbon Antonio5674,Marcaccio Massimo89104,Pisani Michela1112234,Dalzini Annalisa5674,Ussano Eleonora89104,Bortolus Marco567413,Stipa Pierluigi1112234,Astolfi Paola1112234

Affiliation:

1. Department of Life and Environmental Sciences

2. Università Politecnica delle Marche

3. I-60131 Ancona

4. Italy

5. Department of Chemical Sciences

6. Università di Padova

7. I-35131 Padova

8. Department of Chemistry “G. Ciamician”

9. Università di Bologna

10. I-40126 Bologna

11. Department of Materials

12. Environmental Sciences and Urban Planning

13. Department of Material Sciences

Abstract

Fighting lipid peroxidation on its own ground: the antioxidant activity of new synthesized lipid-functionalized nitroxides is maximized in the PUFA region and correlates with the nitroxide location within the lipid bilayer as found by EPR spectroscopy.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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