Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis-Reference-Cited by-同舟云学术

Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis

Published:2021 Issue:1 Volume:12 Page:362-372
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhan Zi-Ying¹²³⁴⁵,Wu Mei¹²³⁴⁵,Shang Yue¹²³⁴⁵,Jiang Min¹²³⁴⁵,Liu Jian¹²³⁴⁵,Qiao Chun-Ying¹²³⁴⁵,Ye Huan¹²³⁴⁵,Lin Yong-Ce¹²³⁴⁵,Piao Mei-Hua¹²³⁴⁵,Sun Rong-Hui¹²³⁴⁵,Zhang Zhi-Hong¹²³⁴⁵,Jiao Jing-Ya¹²³⁴⁵,Wu Yan-Ling¹²³⁴⁵,Nan Ji-Xing¹²³⁴⁵^ORCID,Lian Li-Hua¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Natural Medicines of the Changbai Mountain

2. Ministry of Education

3. College of Pharmacy

4. Yanbian University

5. Yanji

Abstract

Taxifolin ameliorated steatohepatitis induced by long-term HFD feeding plus alcohol binge through modulation of SREBP1 and PPARγ, targeting pyroptotic inflammation related IL-1β release and Caspase-1 activation.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Education Department of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02653K

Reference45 articles.

1. Alcohol and mitochondria: A dysfunctional relationship