Efficient reduction of fibrous capsule formation around silicone breast implants densely grafted with 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers by heat-induced polymerization

Author:

Kang Sunah12345,Kim Jungah12345,Kim Seulah12345,Wufuer Maierdanjiang6785,Park Sohyun12345,Kim Youngmin910385,Choi Dongkil12345,Jin Xian6785,Kim Yumin12345,Huang Yan910385,Jeon Byoungjun1112345,Choi Tae Hyun678513,Park Ji-Ung614155,Lee Yan12345ORCID

Affiliation:

1. Department of Chemistry

2. College of Natural Sciences

3. Seoul National University

4. Seoul 08826

5. Republic of Korea

6. Department of Plastic and Reconstructive Surgery

7. Seoul National University College of Medicine

8. Seoul 03080

9. Interdisciplinary Program in Stem Cell Biology

10. College of Medicine

11. Interdisciplinary Program in Bioengineering

12. College of Engineering

13. Institute of Human-Environment Interface Biology

14. Seoul National University Boramae Medical Center

15. Seoul 07061

Abstract

This article presents the efficacy of heat-induced MPC-grafting against excessive fibrous capsule formation and related inflammation in tissues surrounding silicone breast implants inserted in a pig model.

Funder

National Research Foundation of Korea

Ministry of Health and Welfare

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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