Armoring a liposome-integrated tissue factor with sacrificial CaCO<sub>3</sub> to form potent self-propelled hemostats-Reference-Cited by-同舟云学术

Armoring a liposome-integrated tissue factor with sacrificial CaCO₃ to form potent self-propelled hemostats

Published:2023 Issue:12 Volume:11 Page:2778-2788
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Liu Chengkun¹,Shi Zhuang¹,Zhu Jingyan¹,Liu Chang¹,Liu Xiaodan¹,Khan Naseer Ullah¹,Liu Shihai²,Wang Xiaojuan¹^ORCID,Wang Xiaoqiang¹^ORCID,Huang Fang¹^ORCID

Affiliation:

1. State Key Laboratory of Heavy Oil Processing & College of Chemistry and Chemical Engineering, China University of Petroleum (East China), 66 West Changjiang Road, Qingdao, Shandong 266580, China

2. Medical Research Center, the Affiliated Hospital of Qingdao University, Qingdao, Shandong 266550, China

Abstract

A self-propelled nanoparticle system composed of a tissue factor (TF) integrated into a liposome and a CaCO3 shell was developed, showing superior hemostatic capacity by delivering the lipidated TF deep into bleeding wounds with good biocompatibility.

Funder

Key Technology Research and Development Program of Shandong

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB02140D

Reference48 articles.

1. Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding

2. The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition