Synthesis and structure of nickel(ii) thiocarboxamide complexes: effect of ligand substitutions on DNA/protein binding, antioxidant and cytotoxicity-Reference-Cited by-同舟云学术

Synthesis and structure of nickel(ii) thiocarboxamide complexes: effect of ligand substitutions on DNA/protein binding, antioxidant and cytotoxicity

Published:2015 Issue:58 Volume:5 Page:46760-46773
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Raj Kumar Ramasamy¹²³,Mohamed Subarkhan Mohamed Kasim¹²³,Ramesh Rengan¹²³

Affiliation:

1. School of Chemistry Bharathidasan University

2. Tiruchirappalli 620 024

3. India

Abstract

Four Ni(ii) thiocarboxamide complexes were synthesized and characterized. The effect of ligand substitution on DNA and protein binding is described. The complexes exhibit excellent radical scavenging abilities and show better cytotoxicity against HeLa and MG-63 cell lines.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06112A

Reference68 articles.

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