An insight into carvedilol solid forms: effect of supramolecular interactions on the dissolution profiles
Author:
Affiliation:
1. Instituto de Química
2. Universidade Federal Fluminense
3. Niterói, Brazil
4. Laboratório de Sistemas Farmacêuticos Avançados
5. Complexo Tecnológico de Medicamentos – Farmanguinhos
6. Fundação Oswaldo Cruz
7. Rio de Janeiro, Brazil
Abstract
Carvedilol polymorph III, with higher melting point and dissolution rate than polymorph II, presents a potential strategy for carvedilol development.
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/CE/C3CE42403K
Reference35 articles.
1. D. J. W. Grant , in Polymorphism in Pharmaceutical Solids , ed. H. G. Brittain , Marcel Dekker , New York , 1999 , pp. 1–33
2. Polymorphism: The Same and Not Quite the Same
3. Concomitant Polymorphs
4. Impact of solid state properties on developability assessment of drug candidates
5. Diversity in Single- and Multiple-Component Crystals. The Search for and Prevalence of Polymorphs and Cocrystals
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