DNA binding, molecular docking and apoptotic inducing activity of nickel(ii), copper(ii) and zinc(ii) complexes of pyridine-based tetrazolo[1,5-a]pyrimidine ligands

Author:

Haleel A.123,Arthi P.123,Dastagiri Reddy N.456,Veena V.756,Sakthivel N.756,Arun Y.8910,Perumal P. T.8910,Kalilur Rahiman A.123

Affiliation:

1. Post-Graduate and Research Department of Chemistry

2. The New College (Autonomous)

3. Chennai-600 014, India

4. Department of Chemistry

5. Pondicherry University

6. Pondicherry-605 014, India

7. Department of Biotechnology

8. Organic Chemistry Division

9. CSIR-Central Leather Research Institute

10. Chennai-600 020, India

Abstract

The biological activity of metal(ii) complexes of tetrazolo[1,5-a]pyrimidine ligands show that the copper(ii) complexes may act as promising anticancer agents.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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