Heterobimetallic propargyl gold complexes with π-bound copper or silver with enhanced anticancer activity
Author:
Affiliation:
1. Departamento de Química Inorgánica
2. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH)
3. CSIC-Universidad de Zaragoza
4. 50009 Zaragoza
5. Spain
6. Departamento de Bioquímica y Biología Celular
7. Universidad de Zaragoza-CSIC
Abstract
Heterometallic propargyl gold species in which copper or silver is bound to the triple bond were prepared. The bimetallic complexes had improved activities compared to the mononuclear gold complexes, suggesting a possible synergy between the two metal centres within the cell.
Funder
Ministerio de Ciencia e Innovación
Gobierno de Aragón
European Social Fund
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT02113J
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