Wound healing properties of magnesium mineralized antimicrobial nanofibre dressings containing chondroitin sulphate – a comparison between blend and core–shell nanofibres

Author:

Leung Chak Ming12345,Dhand Chetna12346,Mayandi Venkatesh12347,Ramalingam Raghavendra8910119,Lim Fui Ping1213141516,Barathi Veluchamy Amutha1234,Dwivedi Neeraj6171810,Orive Gorka1920212223,Beuerman Roger W.123424,Ramakrishna Seeram2515264ORCID,Toh Yi-Chin52742829ORCID,Loh Xian Jun303132334ORCID,Verma Navin Kumar123434ORCID,Chua Alvin Wen Choong35363437ORCID,Lakshminarayanan Rajamani123424ORCID

Affiliation:

1. Anti-Infectives Research Group

2. Singapore Eye Research Institute

3. Singapore 169856

4. Singapore

5. NUS Graduate School for Integrative Sciences & Engineering

6. Microfluidics & MEMS Centre

7. School of Biological Sciences

8. Center for Environmental Nuclear Research

9. SRM Institute of Science and Technology

10. India

11. Department of Physics and Nanotechnology

12. Alice Lee Centre for Nursing Studies

13. Yong Loo Lin School of Medicine

14. Clinical Research Centre

15. National University of Singapore

16. Singapore 117597

17. CSIR-Advanced Materials and Processes Research Institute (CSIR-AMPRI)

18. Bhopal 462026

19. NanoBioCel Group

20. Laboratory of Pharmaceutics

21. School of Pharmacy

22. University of the Basque Country UPV/EHU

23. Vitoria-Gasteiz 01006

24. Ophthalmology and Visual Sciences Academic Clinical Program

25. Center for Nanofibres & Nanotechnology

26. Singapore 119077

27. National University of Singapore 117456

28. Department of Biomedical Engineering

29. National University of Singapore 117581

30. Institute of Materials Research and Engineering (IMRE)

31. Agency for Science

32. Technology and Research (A*STAR)

33. Singapore 138634

34. Lee Kong Chian School of Medicine

35. Department of Plastic Reconstructive & Aesthetic Surgery

36. Singapore General Hospital

37. Skin Bank Unit

Abstract

Effect of chondroitin sulphate incorporated PCL/gelatin as blends or core–shell composite nanofibres are compared in terms of their biocompatibility for skin cells and wound healing in porcine model of partial thickness burns.

Funder

National Research Foundation Singapore

National Medical Research Council

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Lee Kong Chian School of Medicine, Nanyang Technological University

Agency for Science, Technology and Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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