An efficient cyclization of lapachol to new benzo[h]chromene hybrid compounds: a stepwisevs.one-pot esterification-click (CuAAC) study-Reference-Cited by-同舟云学术

An efficient cyclization of lapachol to new benzo[h]chromene hybrid compounds: a stepwisevs.one-pot esterification-click (CuAAC) study

Published:2018 Issue:24 Volume:42 Page:19591-19599
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

F. de la Torre Alexander¹²³⁴⁵^ORCID,Ali Akbar⁶⁷⁸,Westermann Bernhard⁹¹⁰¹¹¹²^ORCID,Schmeda-Hirschmann Guillermo¹³¹⁴¹⁵⁵,Walter Pertino Mariano¹³¹⁴¹⁵⁵^ORCID

Affiliation:

1. Departamento de Química Orgánica

2. Facultad de Ciencias Químicas

3. Universidad de Concepción

4. Concepción

5. Chile

6. Department of Chemistry

7. University of Sargodha

8. Pakistan

9. Department of Bioorganic Chemistry

10. Leibniz-Institute of Plant Biochemistry

11. Halle

12. Germany

13. Instituto de Química de Recursos Naturales

14. Universidad de Talca

15. Talca

Abstract

Comparison of one-potvs.stepwise esterification of lapachol to obtain highly diversified heterocycles. Whereas the one-pot esterification leads to mono esterified lapachol, the tandem approach generated benzo[h]chromene.

Funder

Fondo Nacional de Desarrollo Científico y Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ03699C

Reference30 articles.

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4. Ruthenium(II)/triphenylphosphine complexes: An effective way to improve the cytotoxicity of lapachol

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