Novel synthesis and cytotoxic activity of 1,4-disubstituted 3-methylidene-3,4-dihydroquinolin-2(1H)-ones-Reference-Cited by-同舟云学术

Novel synthesis and cytotoxic activity of 1,4-disubstituted 3-methylidene-3,4-dihydroquinolin-2(1H)-ones

Published:2015 Issue:95 Volume:5 Page:78324-78335
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pięta Marlena¹²³⁴,Kędzia Jacek¹²³⁴,Janecka Anna⁵⁶⁷⁴,Pomorska Dorota K.⁵⁶⁷⁴,Różalski Marek⁸⁶⁹⁴,Krajewska Urszula⁸⁶⁹⁴,Janecki Tomasz¹²³⁴

Affiliation:

1. Institute of Organic Chemistry

2. Lodz University of Technology

3. 90-924 Łódź

4. Poland

5. Department of Biomolecular Chemistry

6. Medical University of Łódź

7. 92-215 Łódź

8. Department of Pharmacutical Biochemistry

9. 90-151 Łódź

Abstract

1,4-Disubstituted 3-methylidene-3,4-dihydroquinolin-2(1H)-ones were efficiently synthesized using a Horner–Wadsworth–Emmons approach and their cytotoxic activity was evaluated.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA16673J

Reference20 articles.

1. The Renaissance of α-Methylene-γ-butyrolactones: New Synthetic Approaches

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3. Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential

4. Gelegamines A–E: five new oxindole alkaloids from Gelsemium elegans

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