Tumour associated vasculature-on-a-chip for the evaluation of microbubble-mediated delivery of targeted liposomes-Reference-Cited by-同舟云学术

Tumour associated vasculature-on-a-chip for the evaluation of microbubble-mediated delivery of targeted liposomes

Published:2023 Issue:6 Volume:23 Page:1674-1693
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Bourn Matthew D.¹²^ORCID,Mohajerani Safoura Zahed²,Mavria Georgia²,Ingram Nicola²^ORCID,Coletta P. Louise²,Evans Stephen D.¹^ORCID,Peyman Sally A.¹²^ORCID

Affiliation:

1. School of Physics and Astronomy, University of Leeds, Leeds, LS2 9JT, UK

2. Leeds Institute for Medical Research, Wellcome Trust Brenner Building, St James' University Hospital, Leeds, LS9 7TF, UK

Abstract

Increased accumulation of targeted liposomes was observed in cultures mimicking tumour-associated vasculature, when compared to healthy vasculature cultures. Microbubble-mediated liposome delivery was found to further increase liposome accumulation.

Funder

Engineering and Physical Sciences Research Council

British Heart Foundation

National Institute for Health and Care Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D2LC00963C

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1. Microengineered cancer-on-a-chip platforms to study the metastatic microenvironment