Two Zn(<scp>ii</scp>) coordination polymers with anticancer drug norcantharidin as ligands for cancer chemotherapy-Reference-Cited by-同舟云学术

Two Zn(ii) coordination polymers with anticancer drug norcantharidin as ligands for cancer chemotherapy

Published:2022 Issue:14 Volume:51 Page:5624-5634
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Wang Jia¹,Huang Xiange²,Li Hegen²,Yan Deyue¹^ORCID,Huang Wei¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, P. R. China

2. Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, P. R. China

Abstract

Two Zn(ii) coordination polymers synthesized from norcantharidin and Zn(NO3)2·6H2O can be transformed into nanoparticles for drug delivery. They both can effectively inhibit the growth of Hep3B tumor in vivo with relatively few side effects.

Funder

National Key Research and Development Program of China

Science and Technology Commission of Shanghai Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D2DT00300G

Reference49 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

2. Norcantharidin: research advances in pharmaceutical activities and derivatives in recent years