Application of a simple and rapid LC-MS/MS method for determination of danshensu in human plasma for an oral pharmacokinetic study of Danshen granules in Chinese healthy subjects-Reference-Cited by-同舟云学术

Application of a simple and rapid LC-MS/MS method for determination of danshensu in human plasma for an oral pharmacokinetic study of Danshen granules in Chinese healthy subjects

Published:2014 Issue:6 Volume:6 Page:1956-1962
ISSN:1759-9660
Container-title:Anal. Methods
language:en
Short-container-title:Anal. Methods

Author:

Fu Shujun¹²³,Li Lifeng⁴⁵,Qiu Feng⁶⁷⁸,Wang Baohe⁹¹⁰¹¹,Du Wuxun⁹¹⁰¹¹,Feng Limin⁹¹⁰¹¹

Affiliation:

1. Faculty of Chinese Materia Medica

2. Tianjin University of Traditional Chinese Medicine

3. Tianjin 300193, China

4. Tianjin Public Security Hospital

5. Tianjin 300042, China

6. School of Traditional Chinese Medicine

7. Capital Medical University

8. Beijing 100069, China

9. Traditional Chinese Medicine Department of Internal Medicine of Cardiovascular Center

10. Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine

11. Tianjin 300150, China

Abstract

A simple and rapid LC-ESI-MS method is developed and validated for the determination of danshensu in plasma of Chinese healthy subjects after oral administration of Danshen granules..

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/AY/C3AY42134A

Reference19 articles.

1. Herbs and Dietary Supplements in the Prevention and Treatment of Cardiovascular Disease

2. The pharmacological effects ofSalvia species on the central nervous system

3. New developments in the chemistry and biology of the bioactive constituents of tanshen

4. Quantitative Analysis of the Marker Compounds in Salvia miltiorrihiza Root and Its Phytomedicinal Preparations

5. A novel approach to rapidly explore analytical markers for quality control of Radix Salviae Miltiorrhizae extract granules by robust principal component analysis with ultra-high performance liquid chromatography–ultraviolet–quadrupole time-of-flight mass spectrometry

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