Design, synthesis and evaluation of cytotoxic properties of bisamino glucosylated antitumor ether lipids against cancer cells and cancer stem cells
Author:
Affiliation:
1. Department of Chemistry
2. Faculty of Science University of Manitoba
3. Winnipeg
4. Canada
5. Department of Biochemistry & Medical Genetics, Faculty of Medicine
6. University of Manitoba
Abstract
Glycosylated antitumor ether lipids (GAELs) are a class of amphiphilic antitumor agents that kill cancer cells by a non-apoptotic pathway.
Funder
Natural Sciences and Engineering Research Council of Canada
Canadian Breast Cancer Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00328A
Reference35 articles.
1. Anti-cancer drug resistance: Understanding the mechanisms through the use of integrative genomics and functional RNA interference
2. Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
3. Chemotherapy and Radiotherapy Resistance: Complexity, Reality, and Promise
4. Cancer stem cells: a new framework for the design of tumor therapies
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Synthesis of ether lipids: natural compounds and analogues;Beilstein Journal of Organic Chemistry;2023-09-08
2. The Potential of Novel Lipid Agents for the Treatment of Chemotherapy-Resistant Human Epithelial Ovarian Cancer;Cancers;2022-07-07
3. Cytotoxic capacity of a novel glycosylated antitumor ether lipid in chemotherapy-resistant high grade serous ovarian cancer in vitro and in vivo;Translational Oncology;2021-11
4. ANALYSIS OF CARBOHYDRATES AND GLYCOCONJUGATES BY MATRIX‐ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY: AN UPDATE FOR 2015–2016;Mass Spectrometry Reviews;2021-03-16
5. Access to Galectin-3 Inhibitors from Chemoenzymatic Synthons;The Journal of Organic Chemistry;2020-11-17
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3