Highly selective intramolecular addition of C–N and S–N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles

Author:

Wu Chenglin12345,Zhao Fei678910,Du Yonglei511121314,Zhao Liang511121314,Chen Liang511121314,Wang Jiang511121314,Liu Hong12345

Affiliation:

1. School of Pharmacy

2. China Pharmaceutical University

3. Nanjing 210009

4. China

5. CAS Key Laboratory of Receptor Research

6. Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province

7. Sichuan Industrial Institute of Antibiotics

8. Chengdu University

9. Chengdu 610052

10. People's Republic of China

11. Shanghai Institute of Materia Medica

12. Chinese Academy of Sciences

13. Shanghai 201203

14. P. R. China

Abstract

Palladium-catalyzed highly selective intramolecular addition of C–N and S–N bonds to alkynes has been achieved, and two distinct kinds of functional indoles were synthesized rapidly from the same set of substrates in a catalyst-controlled manner.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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