Improved targeting for photodynamic therapy via a biotin–phthalocyanine conjugate: synthesis, photophysical and photochemical measurements, and in vitro cytotoxicity assay-Reference-Cited by-同舟云学术

Improved targeting for photodynamic therapy via a biotin–phthalocyanine conjugate: synthesis, photophysical and photochemical measurements, and in vitro cytotoxicity assay

Published:2020 Issue:8 Volume:44 Page:3392-3401
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Balçik-Erçin Pelin¹²³⁴⁵^ORCID,Çetin Metin¹²³⁴⁵,Göksel Meltem⁶⁷⁴⁵^ORCID,Durmuş Mahmut¹⁸³⁴⁵

Affiliation:

1. Gebze Technical University

2. Department of Molecular Biology

3. Gebze

4. Kocaeli

5. Turkey

6. Kocaeli University

7. Stem Cell and Gene Therapy Research and Applied Center

8. Department of Chemistry

Abstract

In this study, the peripherally biotin-substituted zinc(ii) phthalocyanine (Pc2) was synthesized as a photosensitizer for the treatment of cancer by photodynamic therapy.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/C9NJ04991F

Reference26 articles.

1. Synthesis, photophysical and photochemical properties of crown ether substituted zinc phthalocyanines

2. Phthalocyanines Covalently Bound to Biomolecules for a Targeted Photodynamic Therapy

3. Targeted photodynamic therapy via receptor mediated delivery systems

4. Differently substituted phthalocyanines: Comparison of calculated energy levels, singlet oxygen quantum yields, photo-oxidative stabilities, photocatalytic and catalytic activities

5. Distribution of Phthalocyanines and Raman Reporters in Human Cancerous and Noncancerous Breast Tissue as Studied by Raman Imaging

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