Conformational impact of aliphatic side chains in local anaesthetics: benzocaine, butamben and isobutamben-Reference-Cited by-同舟云学术

Conformational impact of aliphatic side chains in local anaesthetics: benzocaine, butamben and isobutamben

Published:2020 Issue:45 Volume:56 Page:6094-6097
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Insausti A.¹²³⁴⁵,Calabrese C.¹²³⁴⁵^ORCID,Parra M.¹²³⁴⁵,Usabiaga I.¹²³⁴⁵^ORCID,Vallejo-López M.¹²³⁴⁵,Écija P.¹²³⁴⁵,Basterretxea F. J.¹²³⁴⁵,Grabow J.-U.⁶⁷⁸⁹^ORCID,Caminati W.¹⁰¹¹¹²¹³^ORCID,Lesarri A.¹⁴¹⁵¹⁶⁵^ORCID,Cocinero E. J.¹²³⁴⁵^ORCID

Affiliation:

1. Departamento de Química Física

2. Facultad de Ciencia y Tecnología

3. Universidad del País Vasco (UPV/EHU)

4. Leioa

5. Spain

6. Institut für Physikalische Chemie und Elektrochemie

7. Gottfried Wilhelm Leibniz Universität Hannover

8. Hannover

9. Germany

10. Dipartimento di Chimica “G. Ciamician”

11. Università di Bologna

12. Bologna 40126

13. Italy

14. Departamento de Química Física y Química Inorgánica – IU CINQUIMA

15. Universidad de Valladolid

16. Valladolid

Abstract

A comprehensive conformational analysis and the impact of side chains on local anaesthetics in the case of benzocaine, butamben and isobutamben.

Funder

Euskal Herriko Unibertsitatea

Deutsche Forschungsgemeinschaft

Eusko Jaurlaritza

Consejo Superior de Investigaciones Científicas

Ministerio de Ciencia e Innovación

Fundación BBVA

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC00760A

Reference27 articles.

1. Molecular Determinants of State-Dependent Block of Na + Channels by Local Anesthetics

2. Local Anesthetics: Review of Pharmacological Considerations

3. Advances in Targeting Voltage-Gated Sodium Channels with Small Molecules

4. Molecular Mechanisms of Local Anesthesia

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