Effects of lunar dust simulant on cardiac function and fibrosis in rats-Reference-Cited by-同舟云学术

Effects of lunar dust simulant on cardiac function and fibrosis in rats

Published:2019 Issue:4 Volume:8 Page:499-508
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Sun Yan¹²³⁴⁵^ORCID,Zhang Lu⁶⁷⁸⁹⁴,Liu Jinguo¹⁰¹¹⁸¹²⁴^ORCID,Zhang Xiaoping⁵¹³¹⁴⁴⁵,Su Yan¹²³⁴,Yin Quanling¹²³⁴,He Shuangxi¹⁵⁹⁴

Affiliation:

1. College of Basic Medical Sciences

2. Shenyang Medical College

3. Shenyang 110034

4. China

5. Lunar and Planetary Science Laboratory

6. Key Laboratory of Space Utilization

7. Technology and Engineering Center for Space Utilization

8. Chinese Academy of Sciences

9. Beijing 100094

10. State Key Laboratory of Robotics

11. Shenyang Institute of Automation

12. Shenyang 110016

13. MUST-Partner Laboratory of Key Laboratory of Lunar and Deep Space Exploration

14. CAS

15. China Astronaut Research and Training Center

Abstract

LDS exposure causes systemic inflammatory lesions that affect autonomic function, leading to inflammatory myocardial fibrosis, and its mechanisms involve the mediation of the Nrf2/NOX4 redox balance.

Funder

Department of Science and Technology of Liaoning Province

National Natural Science Foundation of China

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TX/C8TX00329G

Reference28 articles.

1. Physicochemical properties of respirable-size lunar dust

2. Lunar soil grain size distribution

3. Toxicity of lunar dust

4. Moon Walkers and Urban Pollution

5. Toxicity of lunar dust assessed in inhalation-exposed rats

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