Generation of benzosultams via trifluoromethylation of 2-ethynylbenzenesulfonamide under visible light

Author:

Xiang Yuanchao1234,Kuang Yunyan1234,Wu Jie12345

Affiliation:

1. Department of Chemistry

2. Fudan University

3. Shanghai 200433

4. China

5. State Key Laboratory of Organometallic Chemistry

Abstract

Under visible light irradiation, 2-ethynylbenzenesulfonamides react with Togni's reagent in the presence of a photocatalyst leading to 3-(2,2,2-trifluoroethylidene)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxides in good yields. This transformation proceeds efficiently at room temperature through a photo-initiated trifluoromethylation.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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