Biosynthesis of multifunctional transformable peptides for downregulation of PD-L1-Reference-Cited by-同舟云学术

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Biosynthesis of multifunctional transformable peptides for downregulation of PD-L1

Published:2024 Issue: Volume: Page:
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Di Yufei¹²,Yang Zhiwen¹²^ORCID,Song Gang¹²^ORCID,Shen Qi¹^ORCID,Bai Haotian¹^ORCID,Huang Yiming¹^ORCID,Lv Fengting¹^ORCID,Wang Shu¹²^ORCID

Affiliation:

1. Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China

2. College of Chemistry, University of Chinese Academy of Sciences, Beijing 100049, China

Abstract

A biosynthesized material could realize morphological transformation from globular to fibrous for exposing GO203 peptides, and bind to mucin 1 for immune checkpoint blocking therapy.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC03146F

Reference41 articles.

1. Immunological landscape and immunotherapy of hepatocellular carcinoma

2. Precision Medicine in Myelodysplastic Syndromes and Leukemias: Lessons from Sequential Mutations

3. Oncology Meets Immunology: The Cancer-Immunity Cycle

4. Regulating Signal Pathway Triggers Circular Reactive Oxygen Species Production to Augment Oxidative Stress with Enzyme-Activated Nanoparticles

5. Recent advances and discoveries in the mechanisms and functions of CAR T cells

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