An activity-based fluorescent probe and its application for differentiating alkaline phosphatase activity in different cell lines

Author:

He Yong12345,Yu Junli6735,Hu Xiangzi12345,Huang Shumei12345,Cai Lili12345,Yang Liu8910511,Zhang Huatang12345ORCID,Jiang Yin12345,Jia Yongguang1213145ORCID,Sun Hongyan8910511ORCID

Affiliation:

1. School of Chemical Engineering and Light Industry and School of Biomedical and Pharmaceutical Sciences

2. Guangdong University of Technology

3. Guangzhou

4. Guangdong

5. China

6. Department of Ultrasonography

7. The Sixth Affiliated Hospital of Sun Yat-sen University

8. Department of Chemistry and Center of Super-Diamond and Advanced Films (COSDAF)

9. City University of Hong Kong

10. Kowloon

11. Chengdu Research Institute

12. National Engineering Research Center for Tissue Restoration and Reconstruction

13. South China University of Technology

14. Guangzhou 510006

Abstract

An activity-based fluorescent probe with the characteristics of AIE + ESIPT has been reported for differentiating the alkaline phosphatase activity in different cell lines.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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