A tumor-mitochondria dual targeted aza-BODIPY-based nanotheranostic agent for multimodal imaging-guided phototherapy

Author:

Chen Dapeng1234,Zhang Jiaojiao1234,Tang Yunyun1234,Huang Xiaoyu1234,Shao Jinjun1234ORCID,Si Weili1234,Ji Jun5678,Zhang Qi9234,Huang Wei123410ORCID,Dong Xiaochen1234ORCID

Affiliation:

1. Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM)

2. Nanjing Tech University (NanjingTech)

3. Nanjing 211800

4. China

5. Nanjing Stomatological Hospital

6. Medical School of Nanjing University

7. Nanjing 210008

8. P. R. China

9. School of Pharmaceutical Sciences

10. Shaanxi Institute of Flexible Electronics (SIFE)

Abstract

Mitochondria targeted phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has excelled as an effective approach among other non-specific techniques for its high selectivity, non-invasiveness and low systemic toxicity.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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