Biological evaluation and molecular modelling of didanosine derivatives-Reference-Cited by-同舟云学术

Biological evaluation and molecular modelling of didanosine derivatives

Published:2014 Issue:5 Volume:5 Page:622-631
ISSN:2040-2503
Container-title:Med. Chem. Commun.
language:en
Short-container-title:Med. Chem. Commun.

Author:

Ravetti Soledad¹²³⁴⁵,De Candia Cristian A.⁶⁷⁸⁹¹⁰,Gualdesi María S.¹²³⁴⁵,Pampuro Sandra⁶⁷⁸⁹¹⁰,Turk Gabriela⁶⁷⁸⁹¹⁰,Quevedo Mario A.¹²³⁴⁵,Briñón Margarita C.¹²³⁴⁵

Affiliation:

1. Departamento de Farmacia

2. Facultad de Ciencias Químicas

3. Ciudad Universitaria

4. Universidad Nacional de Córdoba

5. 5000 Córdoba, Argentina

6. Instituto de Investigaciones Biomédicas en Retrovirus y SIDA

7. INBIRS

8. Facultad de Medicina

9. Universidad de Buenos Aires

10. Argentina

Abstract

These prodrugs of DDI with increased lipophilicity and good antiviral performance should be of interest in HIV therapy.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MD/C4MD00003J

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5. Structural Insights into the Inhibition of Cytosolic 5′-Nucleotidase II (cN-II) by Ribonucleoside 5′-Monophosphate Analogues

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