Evaluation of the neuroprotective effect of EGCG: a potential mechanism of mitochondrial dysfunction and mitochondrial dynamics after subarachnoid hemorrhage
Author:
Affiliation:
1. College of Life Science
2. Henan Normal University
3. Xinxiang 453007
4. PR China
5. Department of Neurosurgery
6. the First Affiliated Hospital of Xinxiang Medical University
7. Weihui
8. China
Abstract
(−)-Epigallocatechin-3-gallate (EGCG), the main bioactive component of tea catechins, exhibits broad-spectrum health efficacy against mitochondrial damage after subarachnoid hemorrhage (SAH).
Funder
Natural Science Foundation of Henan Province
Henan Normal University
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO01497C
Reference50 articles.
1. Reduced prostate cancer risk with green tea and epigallocatechin 3-gallate intake among Hong Kong Chinese men
2. Beneficial Effects of Dietary EGCG and Voluntary Exercise on Behavior in an Alzheimer's Disease Mouse Model
3. Tea Catechins and Polyphenols: Health Effects, Metabolism, and Antioxidant Functions
4. Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues11Abbreviations: COX, cyclooxygenase; LOX, lipoxygenase; EGCG, (-)-epigallocatechin-3-gallate; EGC, (-)-epigallocatechin; ECG, (-)-epicatechin-3-gallate; EC, (-)-epicatechin; TF, theaflavin; TF3-G, theaflavin 3-gallate; TF3′-G, theaflavin 3′-gallate; TFdiG, theaflavin 3,3′-digallate; PGE2, prostaglandin E2; HETE, hydroxyeicosatetraenoic acid; HHT, 12-hydroxyheptadecatrienoic acid; and TBX, thromboxane.
5. EGCG protective mitochondrial dysfunction after subarachnoid haemorrhage via inhibition p38 α pathway
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